Colorado psilocybin healing centers: how they work, and every listed center

Is psilocybin legal in Colorado?

Yes, for adults 21 and older, within limits. Voters approved Proposition 122, the Natural Medicine Health Act, in November 2022, and SB23-290 set the rules in 2023. Under state law:

• Personal use is legal. Adults 21+ can possess, use and grow natural psilocybin mushrooms. Since August 12, 2026, sharing with another adult counts as personal use only when no money changes hands and the mushrooms are consumed at the time they're shared; handing them off for later use no longer qualifies.
• Selling is not. There are no retail stores, and selling mushrooms outside the licensed system remains a crime. Under 21, possession is a drug petty offense.
• Healing centers are the licensed option. You pay for a facilitated session; the psilocybin is included and taken on site.
• Federal law still applies. Psilocybin remains Schedule I, so don't carry it across state lines or onto federal land.

How a healing center session works

Healing centers are licensed by the Department of Revenue's Natural Medicine Division, and the facilitators who guide sessions are licensed separately by the Department of Regulatory Agencies (DORA). A session generally includes screening and preparation with a facilitator, the administration session itself at the center, and integration support afterward.

• Two license types. Standard healing centers and smaller "micro" healing centers, which are often run by facilitators themselves.
• Psilocybin comes with the session. In a May 2026 bulletin the Natural Medicine Division reminded centers that selling psilocybin separately was prohibited and that the fee for services includes the cost of the natural medicine. HB26-1325 then created a limited sales license that lets a business co-owned and co-located with a healing center sell psilocybin to participants for use during their sessions. Either way, nothing is sold to take home.
• Check the facilitator. You can confirm a facilitator's license with DORA's online license lookup.
• Cost. Prices are set by each center and have generally run into the thousands of dollars for a full program. Ask what's included (preparation, number of sessions, integration) before you book. For comparison, a 2026 study found a median of about $1,900 per session in Oregon.

Colorado by the numbers

• March 31, 2025: the state issued its first healing center license, to The Center Origin in Denver.
• January 2026: the Natural Medicine Division reported 34 licensed healing centers (25 micro and 9 standard), 13 cultivation facilities, 7 product manufacturers and 1 testing lab, from 80 business applications.
• 2025 sessions: in a voluntary early count, healing centers reported serving 109 participants in 2025, in 89 solo sessions and 17 group sessions, in counties including Boulder, Douglas, Eagle, Jefferson and Pitkin. Required annual reporting will give fuller numbers.

What changed in 2026

• SB26-031 (signed April 20, 2026) clears the way for FDA-approved, federally rescheduled psilocybin medicines to be prescribed in Colorado.
• HB26-1325 (signed June 4, 2026, effective August 12, 2026) authorizes an ibogaine research pilot at up to five sites, funded by donations, and changes the natural medicine program: it narrows sharing to mushrooms consumed at the time they're shared, bans advertising natural medicine and paid support services, and creates a limited sales license for businesses co-located with healing centers. A petition drive to put the sharing change to voters didn't make the November 2026 ballot.

Every healing center in Colorado's directory

These are the 44 healing centers listed in the Healing Center Directory that the Natural Medicine Division publishes with center owners, as of October 20, 2026. Listing is not an endorsement, the directory may include centers that are no longer operating, and some licensed centers may not be listed. Confirm a center's license and a facilitator's license before booking.

Source: Colorado Natural Medicine Division Healing Center Directory, linked from the Division's "Accessing regulated natural medicine" page. Duplicate entries were merged.

Personal use: what's allowed and what isn't

• Adults 21+ may grow psilocybin mushrooms at home for personal use.
• Sharing is narrow: no payment, trades or "donations" tied to the mushrooms, and since August 2026 the mushrooms must be consumed when they're shared.
• Don't use in public, and don't drive impaired.
• Cities such as Denver add their own rules for licensed businesses; Denver's FAQ explains them.

Planning a visit from Denver? See our Denver guide. Comparing programs? Oregon's works differently: see the Oregon guide.

Frequently asked questions